Liv Hair and Skin Clinic

Skin & Aesthetic Clinic · Harley Street

Polynucleotides – Plinest polynucleotide

£450

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Polynucleotides – Plinest polynucleotide

Plinest is a polynucleotide treatment used to support skin and scalp quality. Polynucleotides are purified chains derived from natural sources that work with the skin’s own repair processes. Delivered through a series of small injections, the treatment helps to hydrate the tissue and improve the condition of the treated area over a planned course. At Liv Hair & Skin Clinic on Harley Street, it is carried out by clinicians following a full medical assessment.

Plinest may be considered for concerns affecting the face, the delicate skin around the eyes, the neck and the scalp. It is often chosen by people looking to address:

  • Overall skin quality, texture and firmness
  • Fine, crepey skin, including the under-eye area
  • Scalp and hair condition where appropriate

Treatment sessions are usually short and any plan is personalised to your goals. Some redness, mild swelling or small marks at the injection points can occur and typically settle within a few days. Your clinician will provide clear aftercare guidance, which may include avoiding heavy exercise, heat and make-up on the treated area for a short period. A course of sessions is commonly recommended, with the details confirmed for you individually.

Suitability, expected outcomes and your treatment plan are assessed at a free consultation at 19 Harley Street, London.

All treatments are assessed and confirmed at a private consultation. Suitability, risks and aftercare are discussed in person at 19 Harley Street, London.

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Frequently asked questions

What is Plinest and what does it do?

Plinest is a polynucleotide treatment made from purified DNA fragments. Delivered through fine injections, it supports the skin's own repair to improve hydration, elasticity and texture. It is often chosen for tired or crepey skin and the delicate under-eye area. Suitability is assessed at consultation.

How many Plinest sessions will I need?

A typical course is two to three sessions spaced around two to three weeks apart, then maintenance every few months. Because it works by supporting repair, the improvement builds gradually. Your clinician tailors the plan to your skin at consultation.

Is there downtime?

Downtime is usually minimal. You may have small injection points, mild redness, slight swelling or occasional bruising for a day or two, particularly under the eyes. We advise avoiding make-up, alcohol and the gym for the rest of the day.

When will I see results and how long do they last?

Many people notice improved hydration and a fresher look within two to four weeks, with firmness and texture continuing to improve. Results are typically maintained for several months with periodic top-ups, and individual responses vary.

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